The main objective of this course is to lecture students on Biochemistry of digestion of nucleic acids. Degradation of purine and pyrimidine ribonucleotide and deoxyribonucleotide. Biosynthesis of the purine/pyrimidine ribonucleotide (via the salvage and the de-novo pathways) and their regulation. Biosynthesis and regulation of deoxyribonucleotide and nucleotide coenzymes.  Disorders of nucleotide metabolism.